Additionally, Li et al. have exposed the upregulation of PI3K/AKT pathway encourages the expressions of placental growth component (PlGF) and C-X-C Motif Chemokine Ligand one (CXCL1) in lung most cancers stem cells, which further more promote angiogenesis [59]. CCPlenty of paracrine factors secreted by MSCs are ligands for receptors that activate P

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